FIELDABLE MASS SPECTROMETRY FOR FORENSIC SCIENCE, HOMELAND SECURITY, AND DEFENSE APPLICATIONS
| Autor: | Ashley R. Stelmack, Jessica M. Holtz, Phoebe C. Clowser, Kenyon Evans-Nguyen, Christopher C. Mulligan |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Chemistry 010401 analytical chemistry Forensic chemistry Homeland security Condensed Matter Physics Computer security computer.software_genre Mass spectrometry 01 natural sciences General Biochemistry Genetics and Molecular Biology 0104 chemical sciences Analytical Chemistry 03 medical and health sciences 030104 developmental biology Chemical warfare computer Spectroscopy |
| Zdroj: | Mass spectrometry reviewsREFERENCES. 40(5) |
| ISSN: | 1098-2787 |
| Popis: | Mass spectrometry is commonly used in forensic chemistry laboratories for sensitive, definitive analysis. There have been significant efforts to bring mass spectrometry analysis on-site through the development of ruggedized, fieldable instruments. Testing samples in the field is of particular interest in forensic science, homeland security, and defense applications. In forensic chemistry, testing seized drugs in the field can significantly improve efficiencies in processing of related criminal cases. The screening of passengers and luggage at transportation hubs is a critical need for homeland security for which mass spectrometry is well suited to provide definitive answers with low false positive rates. Mass spectrometry can yield reliable data for military personnel testing sites for potential chemical weapons release. To meet the needs of the forensic and security communities fieldable mass spectrometers based on membrane inlet systems and hybrid gas chromatography systems have been developed and commercialized. More recently developed ambient ionization mass spectrometry methods can eliminate the time, equipment, and expertise associated with sample preparation, and so are especially appealing for on-site analysis. We describe the development of fieldable mass spectrometry systems, with emphasis on commercially available systems that have been deployed for on-site analysis of seized drugs, chemical warfare agents, explosives, and other analytes of interest to the forensic and security communities. © 2020 John Wiley & Sons Ltd. Mass Spec Rev. |
| Databáze: | OpenAIRE |
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