Hemostatic treatment after tooth extraction in a patient with factor V deficiency
| Autor: | T. Osaki, Y. Tatemoto, T. Yokoyama |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Molar medicine.medical_specialty Factor V Deficiency Fibrin Tissue Adhesive Postoperative Hemorrhage Fibrinogen medicine Humans Fibrin glue General Dentistry Coagulation Disorder biology business.industry Factor V Factor XIII Hemostasis Surgical Surgery Otorhinolaryngology Dental Care for Chronically Ill Hemostasis Tooth Extraction biology.protein Female business medicine.drug |
| Zdroj: | Oral Diseases. 3:196-198 |
| ISSN: | 1354-523X |
| DOI: | 10.1111/j.1601-0825.1997.tb00036.x |
| Popis: | BACKGROUND: Factor V deficiency is a very rare hereditary coagulation disorder and tooth extraction in the patient with factor V deficiency has not been reported except in one case. PATIENTS AND TREATMENT: A 38-year-old woman with factor V deficiency was referred for extraction of the impacted lower third molar. After intravenous administration of frozen fresh plasma (FFP) and recognition of an increase of factor V level from 1–31%, upper and lower third molars were extracted. Eighteen and 48 h after the extraction, factor V was intermittently supplemented by injection of 4 and 2 units of FFP, respectively, and factor V was maintained above 12%. To form fast coagula and to protect the wound, the lower extraction socket was filled with a fibrin glue composed of factor XIII and fibrinogen (Beriplast® P) and a plastic splint was applied. The wound was healed and epithelized within 2 weeks after the extraction without any bleeding or infectious consequences. CONCLUSION: Extraction in the patient with factor V hereditary deficiency is safely performed by both supplementation of factor V and application of local hemostasis. |
| Databáze: | OpenAIRE |
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