Suppressing effect of Lactobacillus casei administration on the urinary mutagenicity arising from ingestion of fried ground beef in the human
| Autor: | Toshiko Hayatsu, Hikoya Hayatsu |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male endocrine system Cancer Research Lactobacillus casei Meat Urinary system Population Urine Oral administration Ingestion Anticarcinogenic Agents Humans Food science Cooking education Carcinogen education.field_of_study biology Chemistry Mutagenicity Tests digestive oral and skin physiology fungi food and beverages biology.organism_classification Lacticaseibacillus casei Oncology Toxicity Carcinogens Female Powders Antimutagen Mutagens |
| Zdroj: | Cancer letters. 73(2-3) |
| ISSN: | 0304-3835 |
| Popis: | It is known that the ingestion of cooked meat which contains carcinogenic heterocyclic amines causes increase in urinary mutagenicity in humans. Using 6 healthy non-smokers, we examined the effect of 3-week oral administration of Lactobacillus casei (bacilli commonly present in yoghurt), on the urinary mutagenicity derived from ingestion of fried ground beef. Comparison of the urinary mutagenicity found before and after the L. casei treatment showed that the treatment resulted in a decrease (6–67%, average 47.5%) of the mutagenicity. This suppressing effect is possibly related to the changes in the intestinal microflora population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|