Dual modality endomicroscope with optical zoom capability
| Autor: | Teresa L. Southard, Watt W. Webb, Julie Bentley, David R. Rivera, Robert S. Weiss, John A. Stupinski, Dimitre G. Ouzounov, Chris Xu, Wendy O. Williams, Kelly H. Hume |
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| Rok vydání: | 2013 |
| Předmět: |
Physics
Modality (human–computer interaction) medicine.diagnostic_test Image quality business.industry Intrinsic fluorescence equipment and supplies Reflectivity Atomic and Molecular Physics and Optics Optics Optical coherence tomography medicine Dual modality Zoom business Endoscopes Catheters and Micro-Optics Image resolution Biotechnology |
| Zdroj: | Biomedical Optics Express. 4:1494 |
| ISSN: | 2156-7085 |
| DOI: | 10.1364/boe.4.001494 |
| Popis: | We present a miniature endomicroscope that combines large field-of-view (FOV) (1.15 mm) reflectance imaging with high-resolution (~0.5 μm) multiphoton intrinsic fluorescence imaging. We acquired in vivo and ex vivo images of unstained normal and tumor-laden tissues by using the large-FOV mode to navigate to the site of interest and then switching to the high-resolution modality to resolve cellular details. |
| Databáze: | OpenAIRE |
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