Control of semaphorin signaling
| Autor: | Geneviève Rougon, Valérie Castellani |
|---|---|
| Přispěvatelé: | Institut de Biologie du Développement de Marseille (IBDM), Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Centre National de la Recherche Scientifique (CNRS), Centre de génétique et de physiologie moléculaire et cellulaire (CGPhiMC), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon |
| Předmět: |
rho GTP-Binding Proteins
MESH: Signal Transduction animal structures Growth Cones MESH: Neurons Guanosine Nerve Tissue Proteins MESH: Semaphorins Semaphorins [SDV.BC]Life Sciences [q-bio]/Cellular Biology Biology MESH: Actins 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Semaphorin Animals Humans MESH: Animals Neuropilins MESH: Nerve Tissue Proteins Receptor Actin 030304 developmental biology Neurons 0303 health sciences MESH: Humans Effector General Neuroscience Plexin MESH: Growth Cones MESH: rho GTP-Binding Proteins Actins 3. Good health Cell biology chemistry nervous system Cytoplasm embryonic structures biology.protein MESH: Cell Adhesion Molecules sense organs biological phenomena cell phenomena and immunity MESH: Neuropilins Transduction (physiology) Neuroscience Cell Adhesion Molecules 030217 neurology & neurosurgery Signal Transduction |
| Zdroj: | ResearcherID Current Opinion in Neurobiology Current Opinion in Neurobiology, Elsevier, 2002, 12 (5), pp.532-41 Current Opinion in Neurobiology, Elsevier, 2002, 12, pp.532-541 Current Opinion in Neurobiology, 2002, 12, pp.532-541 Current Opinion in Neurobiology, 2002, 12 (5), pp.532-41 |
| ISSN: | 0959-4388 |
| Popis: | Receptor complexes for the chemorepellent factors of the semaphorin family activate intracellular pathways that trigger actin rearrangements underlying growth cone collapse and repellent behavior. Some evidence has been provided for a complex and dynamic pattern of interaction between members of the small Rho guanosine triphosphatases and plexin proteins that are the receptor subunits responsible for initiating semaphorin signaling. The characterization of new components of semaphorin receptor complexes, the implication of several distinct classes of cytoplasmic effectors, together with the observation of a variety of processes modulating the semaphorin signal have provided a basis for a much improved, but still intricate view of the semaphorin transduction pathways in neurons. |
| Databáze: | OpenAIRE |
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