Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats
Autor: | V. Ya. Arion, O. V. Belova, A. V. Novoseletskaya, V. I. Sergienko, N. M. Kiseleva, I. V. Zimina, A. N. Inozemtsev, O. V. Bystrova |
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Rok vydání: | 2014 |
Předmět: |
medicine.medical_treatment
Conditioning Classical Spleen Thymus Gland Pharmacology Thymus Extracts General Biochemistry Genetics and Molecular Biology Avoidance learning Memory Avoidance Learning Medicine Animals Rats Wistar Nootropic Agents Thymus extract business.industry Avoidance Conditioning General Medicine Thymectomy Rats medicine.anatomical_structure Organ Specificity Immunology business Peptides |
Zdroj: | Bulletin of experimental biology and medicine. 159(5) |
ISSN: | 1573-8221 |
Popis: | We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.5 mg/kg) during 1 month after surgery restored learning capacity; splenic polypeptides were ineffective. |
Databáze: | OpenAIRE |
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