UV radiation in marine ectotherms: Molecular effects and responses
| Autor: | Jae-Seong Lee, Hans-U. Dahms |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Embryo
Nonmammalian DNA Repair Ultraviolet Rays DNA repair DNA damage Health Toxicology and Mutagenesis Marine Biology Aquatic Science Biology Ecotoxicology medicine.disease_cause medicine Animals integumentary system Ecology fungi Fishes Marine invertebrates Invertebrates Cell biology Germ Cells Fertilization Photoprotection Ectotherm Sperm Motility Metagenomics Toxicogenomics Oxidative stress DNA Damage Nucleotide excision repair |
| Zdroj: | Aquatic Toxicology. 97:3-14 |
| ISSN: | 0166-445X |
| DOI: | 10.1016/j.aquatox.2009.12.002 |
| Popis: | This review summarizes current knowledge on ultraviolet radiation (UVR)-induced cellular and molecular damage in marine ectotherms (invertebrates and fish). UVR impairs sperm motility, reduces fertilization, and causes embryo malformation that in turn affects recruitment and therefore the sustainability of natural populations. The direct molecular effects of UVR are mediated by absorption of certain wavelengths by specific macromolecules and the dissipation of the absorbed energy via photochemical reactions. Most organisms have defense mechanisms that either prevent UVR-induced damage, or mechanisms that repair the damage. Photoprotective pigments, antioxidant defense compounds, and cell cycle development genes are some of the molecules involved in UVR defense. Photoenzymatic repair and nucleotide excision repair are the two primary DNA repair systems in marine ectotherms. We anticipate that toxicogenomic studies will gain importance in UVR research because they can elucidate the primary processes involved in UVR damage and the cellular response to this damage. |
| Databáze: | OpenAIRE |
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