Developmental changes of the fetal and neonatal thyroid gland and functional consequences on the cardiovascular system

Autor:	Ioanna Kotsopoulou, Arpita K. Vyas, Melinda J. Cory, Christina S. Chan, Jawahar Jagarapu, Shamaila Gill, Manjula Mudduluru, Dimitrios Angelis
Rok vydání:	2022
Předmět:	Thyroid Hormones Fetus Pediatrics Perinatology and Child Health Infant Newborn Thyroid Gland Obstetrics and Gynecology Humans Heart
Zdroj:	Journal of perinatology : official journal of the California Perinatal Association. 42(12)
ISSN:	1476-5543
Popis:	Thyroid hormones play an important role in the development and function of the cardiac myocyte. Dysregulation of the thyroid hormone milieu affects the fetal cardiac cells via complex molecular mechanisms, either by altering gene expression or directly by affecting post-translational processes. This review offers a comprehensive summary of the effects of thyroid hormones on the developing cardiovascular system and its adaptation. Furthermore, we will highlight the gaps in knowledge and provide suggestions for future research.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c79e2ebc2b36a40416640eb6d59376 https://pubmed.ncbi.nlm.nih.gov/36376450 Zobrazit plný text záznamu Full text from SpringerLink