Toxic Epidermal Necrolysis: A Dermatologic Emergency and the Role of the Oral and Maxillofacial Surgeon
| Autor: | Brian Wolf, Victor L. Nannini, Rory S. Sadoff |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Adolescent medicine.drug_class Antibiotics Mucocutaneous zone Primary care Malaise 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Humans Oral and Maxillofacial Surgeons Physician's Role Acne business.industry Minocycline medicine.disease Combined Modality Therapy Dermatology Toxic epidermal necrolysis Otorhinolaryngology Epidermal necrosis Stevens-Johnson Syndrome 030220 oncology & carcinogenesis Surgery Emergencies Oral Surgery medicine.symptom business medicine.drug |
| Zdroj: | Journal of Oral and Maxillofacial Surgery. 76:1688-1694 |
| ISSN: | 0278-2391 |
| Popis: | Toxic epidermal necrolysis (TEN) is a rare and severe mucocutaneous disorder characterized by mucosal and epidermal necrosis and sloughing. This potentially life-threatening condition, together with the less severe Stevens-Johnson syndrome, is commonly caused by an immunologic reaction to medications and can lead to many long-term complications. The disorder initially presents with fever, malaise, and painful mucosal ulcerations (most commonly oral) but progresses to widespread cutaneous lesions. A 14-year-old male patient was prescribed minocycline for treatment of his acne by his primary care doctor. Three weeks into the antibiotic treatment, he was admitted in distress, with a diagnosis of Stevens-Johnson syndrome that subsequently progressed to TEN. We present a discussion of the importance of early recognition and diagnosis of this condition by oral and maxillofacial surgeons and a description of our patient's treatment and management during his hospital stay. |
| Databáze: | OpenAIRE |
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