Function of Non-coding RNA in Helicobacter pylori-Infected Gastric Cancer
| Autor: | Chuan Yang, Yulu Bao, Yiyang Hu, Bo Zhou, Chao Wang, Sumin Wang, Huan Yang, Xia Xie, Qiang Luo, Shi-Ming Yang, Yu Huang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
QH301-705.5 non-coding RNA Review medicine.disease_cause Biochemistry Genetics and Molecular Biology (miscellaneous) Biochemistry Helicobacter pylori infection Metastasis 03 medical and health sciences 0302 clinical medicine genetic polymorphisms medicine Molecular Biosciences Biology (General) Molecular Biology biology gastric cancer RNA Cancer chemoresistance Helicobacter pylori biology.organism_classification medicine.disease Non-coding RNA Chronic infection 030104 developmental biology Tumor progression 030220 oncology & carcinogenesis Cancer research Carcinogenesis |
| Zdroj: | Frontiers in Molecular Biosciences, Vol 8 (2021) Frontiers in Molecular Biosciences |
| DOI: | 10.3389/fmolb.2021.649105/full |
| Popis: | Gastric cancer is a common malignant tumor of the digestive system. Its occurrence and development are the result of a combination of genetic, environmental, and microbial factors. Helicobacter pylori infection is a chronic infection that is closely related to the occurrence of gastric tumorigenesis. Non-coding RNA has been demonstrated to play a very important role in the organism, exerting a prominent role in the carcinogenesis, proliferation, apoptosis, invasion, metastasis, and chemoresistance of tumor progression. H. pylori infection affects the expression of non-coding RNA at multiple levels such as genetic polymorphisms and signaling pathways, thereby promoting or inhibiting tumor progression or chemoresistance. This paper mainly introduces the relationship between H. pylori-infected gastric cancer and non-coding RNA, providing a new perspective for gastric cancer treatment. |
| Databáze: | OpenAIRE |
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