Chemokine CXCL14-like immunoreactivity in the αMSH-producing cells and PRL-producing cells of the flat-tailed house gecko pituitary
| Autor: | Toshiharu Yamamoto, Hirohumi Suzuki |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Chemokine Glucose uptake gecko Biology pituitary Internal medicine medicine Animals Myocyte CXCL14 Full Paper General Veterinary Pancreatic islets Lizards Pars intermedia Immunohistochemistry Prolactin reptile Endocrinology medicine.anatomical_structure alpha-MSH Pituitary Gland biology.protein Female Anatomy Chemokines CXC hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.19-0567 |
| Popis: | The distribution pattern of chemokine CXCL14-immunoreactive cells was examined by immunohistochemistry in the pituitary of the gecko Hemidactylus platyurus. Immunoreactive cells were observed in the pars intermedia and pars distalis of the pituitary, but not in the pars nervosa. All α-melanocyte-stimulating hormone (αMSH)-producing cells were immunoreactive for CXCL14 in the pars intermedia. The CXCL14-immunoreactive cells corresponded to prolactin (PRL)-producing cells but not to other adenohypophyseal-hormone-producing cells in the pars distalis. CXCL14 secreted from αMSH-producing cells and PRL-producing cells may regulate insulin release from β cells in the pancreatic islets as well as glucose uptake in the muscle cells together with αMSH and/or PRL. In addition, secreted CXCL14 with αMSH and/or PRL may act as a bioactive factor regulating hormone release in the adenohypophyseal cells of the reptilian pars distalis. |
| Databáze: | OpenAIRE |
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