Randomized clinical trial of soy formula with and without added fiber in antibiotic-induced diarrhea
| Autor: | Geraldine Baggs, Jon A. Vanderhoof, Karin M. Ostrom, Sunil Mehra, A. Wesley Burks |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Dietary Fiber
Male medicine.medical_specialty Randomization Vomiting medicine.drug_class Antibiotics Weight Gain law.invention Animal science Randomized controlled trial law Internal medicine Outcome Assessment Health Care Humans Medicine Fiber business.industry Infant Parallel study Anti-Bacterial Agents Diarrhea Endocrinology Diarrhea Infantile Pediatrics Perinatology and Child Health Female Infant Food Soybeans medicine.symptom Energy Intake business Weight gain |
| Zdroj: | The Journal of Pediatrics. 139:578-582 |
| ISSN: | 0022-3476 |
| DOI: | 10.1067/mpd.2001.118198 |
| Popis: | Objective: The objective of this study was to examine the effects of soy formulas with and without added soy fiber in children who developed diarrhea while receiving antibiotics. Design: In a masked, randomized parallel study, older infants and toddlers were fed commercial soy formulas with or without added soy fiber for 10 days on occurrence of diarrhea during the administration of antibiotics. Subjects were stratified by feeding (formula versus cow’s milk). The primary variables were duration of diarrhea, stool characteristics, and intake. Secondary variables were weight and spit-up. Results: All 45 children who completed the 10-day study received >30% of their caloric intake from formula. Fiber intake from other foods did not differ between groups and averaged 0.5 g/day. Total median fiber intake of the group fed the formula with added fiber was 6.53 g/day. The mean duration of diarrhea was 25.1 ± 5.2 hours for children fed the formula with added fiber and 51.6 ± 10.7 hours for those fed the regular formula ( P = .0013). Conclusion: The duration of antibiotic-induced diarrhea in children fed the soy formula with added soy fiber was significantly reduced. (J Pediatr 2001;139:578-82) |
| Databáze: | OpenAIRE |
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