Virome of US bovine calf serum

Autor: Xiang-Jin Meng, David J. Hurley, Xutao Deng, Eric Delwart, Tung Gia Phan, Tanja Opriessnig, Danielle M. Yugo, Beatrix Kapusinszky, Mohammadreza Sadeghi, Isis Kanevsky, Amelia R. Woolums
Přispěvatelé: Medicum, Klaus Hedman / Principal Investigator, Human Parvoviruses: Epidemiology, Molecular Biology and Clinical Impact, Department of Virology
Rok vydání: 2017
Předmět:
Zdroj: Sadeghi, M, Kapusinszky, B, Yugo, D M, Phan, T G, Deng, X, Kanevsky, I, Opriessnig, T, Woolums, A R, Hurley, D J, Meng, X & Delwart, E 2017, ' Virome of US bovine calf serum ', Biologicals . https://doi.org/10.1016/j.biologicals.2016.12.009
ISSN: 1045-1056
Popis: Using viral metagenomics we analyzed four bovine serum pools assembled from 715 calves in the United States. Two parvoviruses, bovine parvovirus 2 (BPV2) and a previously uncharacterized parvovirus designated as bosavirus (BosaV), were detected in 3 and 4 pools respectively and their complete coding sequences generated. Based on NS1 protein identity, bosavirus qualifies as a member of a new species in the copiparvovirus genus. Also detected were low number of reads matching ungulate tetraparvovirus 2, bovine hepacivirus, and several papillomaviruses. This study further characterizes the diversity of viruses in calf serum with the potential to infect fetuses and through fetal bovine serum contaminate cell cultures. (C) 2017 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.
Databáze: OpenAIRE
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