High levels of fasting glucose and glycosylated hemoglobin values are associated with hyperfiltration in a Spanish prediabetes cohort. The PREDAPS Study

Autor: Gabriel Coll de Tuero, Antonio Rodriguez-Poncelas, Josep Franch-Nadal, Margarita Alonso-Fernández, Antonio José Ortiz Ruiz, Teresa Mur-Marti, Carolina Giráldez-García, Manel Mata-Cases, Enrique Regidor
Rok vydání: 2019
Předmět:
Blood Glucose
Male
endocrine system diseases
Physiology
Kidneys -- Diseases
030232 urology & nephrology
Blood Pressure
Biochemistry
Vascular Medicine
Gastroenterology
Cohort Studies
Endocrinology
0302 clinical medicine
Risk Factors
Chronic Kidney Disease
Odds Ratio
Diabetes diagnosis and management
Medicine
Prediabetes
Prospective cohort study
Diabetis
Multidisciplinary
Diabetes
Fasting
Middle Aged
Nephrology
Hypertension
Cohort
Blood pressure
Hipertensió
Female
Anatomy
Glomerular Filtration Rate
Research Article
Cohort study
Adult
medicine.medical_specialty
HbA1c
Ronyons -- Malalties
Endocrine Disorders
Science
Renal function
030209 endocrinology & metabolism
Pressió sanguínia
Prediabetic State
03 medical and health sciences
Diabetes mellitus
Internal medicine
Diabetes Mellitus
Humans
Obesity
Hemoglobin
Renal Insufficiency
Chronic
Aged
Nutrition
Glycated Hemoglobin
Medicine and health sciences
Renal Physiology
Biology and life sciences
business.industry
Proteins
nutritional and metabolic diseases
Kidneys
Renal System
Odds ratio
medicine.disease
Diagnostic medicine
Diet
Spain
Metabolic Disorders
business
Zdroj: PLoS ONE
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
PLoS ONE, 2019, vol. 14, núm. 9, p. e0222848
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
PLoS ONE, Vol 14, Iss 9, p e0222848 (2019)
ISSN: 1932-6203
Popis: This study aimed to investigate whether different levels of fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) in prediabetes are associated with hyperfiltration. Methods A prospective cohort of 2,022 individuals aged 30–74 years took part in the PREDAPS Study. One cohort of 1,184 participants with prediabetes and another cohort of 838 participants with normal FPG and normal HbA1c were followed for 5 years. Hyperfiltration was defined as an estimated glomerular filtration rate (eGFR) above the age- and gender-specific 95th percentile for healthy control participants, while hypofiltration was defined as an eGFR below the 5th percentile. The prevalence of hyperfiltration was compared for different levels of prediabetes: level 1 of prediabetes: FPG
Databáze: OpenAIRE
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