Electrophilic RhI catalysts for arene H/D exchange in acidic media: Evidence for an electrophilic aromatic substitution mechanism
| Autor: | Robert J. Nielsen, Bradley A. McKeown, Ross Fu, T. Brent Gunnoe, Michael S. Webster-Gardiner, Paige E. Piszel, William A. Goddard |
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| Rok vydání: | 2017 |
| Předmět: |
Steric effects
Denticity 010405 organic chemistry Process Chemistry and Technology chemistry.chemical_element Electrophilic aromatic substitution 010402 general chemistry Photochemistry 01 natural sciences Medicinal chemistry Catalysis 0104 chemical sciences Rhodium chemistry.chemical_compound chemistry Electrophile Trifluoroacetic acid Physical and Theoretical Chemistry |
| Zdroj: | Journal of Molecular Catalysis A: Chemical. 426:381-388 |
| ISSN: | 1381-1169 |
| Popis: | A series of new rhodium (I) complexes supported by bidentate nitrogen-donor ligands with varying electronic and steric properties were synthesized in situ and evaluated for catalytic arene C−H/D activation. In trifluoroacetic acid (HTFA), these complexes are proposed to mediate H/D exchange of arene C−H/D bonds by an electrophilic aromatic substitution mechanism that involves Rh-mediated activation of HTFA (or DTFA). DFT calculations support the proposed pathway for the H/D exchange reactions. |
| Databáze: | OpenAIRE |
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