Cryptococcus neoformans var. grubii Infection in HIV-Seronegative Patients from Northeast India: Report of Two Cases with Review of Literature
| Autor: | Longminder Timung, Basanta Laskar, Jishan Ahmed, Lahari Saikia, Subhalakshmi Das, Reema Nath |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Antifungal Agents Adolescent Veterinary (miscellaneous) 030106 microbiology 030231 tropical medicine Human immunodeficiency virus (HIV) India Skin infection Meningitis Cryptococcal medicine.disease_cause Applied Microbiology and Biotechnology Microbiology 03 medical and health sciences Young Adult 0302 clinical medicine Medical microbiology Amphotericin B HIV Seronegativity parasitic diseases Female patient DNA Ribosomal Spacer medicine Dermatomycoses Humans Fluconazole Cryptococcus neoformans Pregnancy biology Base Sequence Sequence Analysis DNA medicine.disease biology.organism_classification Cryptococcus neoformans var. grubii DNA Intergenic Female Cryptococcal meningitis Agronomy and Crop Science |
| Zdroj: | Mycopathologia. 181(3-4) |
| ISSN: | 1573-0832 |
| Popis: | Cryptococcus neoformans infection can occur in a wide range of hosts ranging from those who are severely immunosuppressed to those who are apparently immunocompetent. Two apparently immunocompetent HIV-seronegative patients with cryptococcal meningitis and multiple skin lesions, both due to C. neoformans var. grubii, are reported. Pregnancy was found as an associated factor in cryptococcal meningitis in a 20-year-old female patient from Arunachal Pradesh. Multiple skin lesions were the presenting feature of an 18-year-old male patient from Dibrugarh, eastern Assam. The organism was identified both phenotypically and by sequencing of ITS1 and ITS2 regions of rRNA gene. The cases are reported because of rarity of this infection in non-HIV-infected patients. |
| Databáze: | OpenAIRE |
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