Rocuronium priming for tracheal intubation in COVID‐19 patients

Autor: Tsutomu Mieda, China Nakamura, Hiroshi Nagasaka, K. Komiyama, Hiroshi Hoshijima, M. Ozaki, Katsushi Doi
Rok vydání: 2020
Předmět:
Zdroj: Anaesthesia Reports
Anaesth Rep
ISSN: 2637-3726
DOI: 10.1002/anr3.12060
Popis: Summary Priming doses of non-depolarising neuromuscular blocking drugs given before administration of anaesthetic agents have been used to hasten the onset of neuromuscular blockade In the settings of coronavirus disease 2019 (COVID-19), this could be used to reduce the apnoeic, and potentially aerosol-generating, window To our knowledge, we report the first cases of tracheal intubation with rocuronium for COVID-19 using the priming principle Both patients needed their tracheas intubated for severe hypoxia using a rapid sequence induction technique with a priming dose of rocuronium Despite adequate pre-oxygenation a sudden, unexpected fall in arterial oxygen saturations was observed in both patients after administration of a priming dose of 2 mg of rocuronium Clinicians should consider this possible risk associated with priming doses of neuromuscular blocking drugs in the management of patients with respiratory failure due to COVID-19
Databáze: OpenAIRE