Endometrial cancer combined with polycystic ovary syndrome in 9 women under 40-years old: A case report
Autor: | Ningwei Li, Xi-Biao Jia, Cen Chen, Hong-jing Wang, Ling-Yun Yang, Pan Xu |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
medicine.medical_specialty endocrine system diseases Medroxyprogesterone General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine young age medicine Carcinoma Vaginal bleeding General Pharmacology Toxicology and Pharmaceutics Young female Gynecology medicine.diagnostic_test business.industry General Neuroscience Endometrial cancer Cancer General Medicine Articles medicine.disease Polycystic ovary 030104 developmental biology Hysteroscopy polycystic ovary syndrome 030220 oncology & carcinogenesis endometrial cancer medicine.symptom business medicine.drug |
Zdroj: | Biomedical Reports |
ISSN: | 2049-9442 2049-9434 |
Popis: | The aim of the present study was to discuss the clinicopathological characteristics of endometrial carcinoma in young females with polycystic ovary syndrome (PCOS), and to review the current literature. A total of 9 patients with histopathologically confirmed endometrial cancer in young females with PCOS at the West China Second Hospital of Sichuan University between December 2007 and September 2013 were included. The clinicopathological characteristics of the patients were analyzed. The age range of the patients was 24-38 years (median age, 29), all of the cases had abnormal vaginal bleeding and endometrioid adenocarcinoma was the most common histopathological subtype observed (8 cases, 88.9%). Of the patients, 2 had well-differentiated cases and 7 patients had moderately differentiated cases. None of the patients received regular PCOS treatments and did not turn up for regular check-ups before they were diagnosed with endometrial carcinoma. Additionally, 7 patients received staging laparotomy with a total abdominal hysterectomy and bilateral salpingo-oophorectomy, 1 patient underwent an endometrial resection under hysteroscopy and the final patient received a high-dose of medroxyprogesterone treatment without surgery. In conclusion, doctors should take into consideration that young women with PCOS may also exhibit an endometrial carcinoma, and diagnosing and treating the endometrial carcinoma as early as possible in the young patients with PCOS is necessary. |
Databáze: | OpenAIRE |
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