Recent advances in chemistry of amino sugars: occurrence, biosynthesis, synthesis and application

Autor: Jadson Farias Silva, Mauricelia Maria de Sousa Mata, Juliano Carlo Rufino Freitas, João Rufino de Freitas Filho, Bruna Martins Guimarães, Aldicéia Luiz de Moura, Ronaldo N. de Oliveira, Josefa Aqueline da Cunha Lima
Rok vydání: 2019
Předmět:
Zdroj: Química Nova v.42 n.6 2019
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 42, Issue: 6, Pages: 642-660, Published: 15 AUG 2019
Química Nova, Vol 42, Iss 6, Pp 642-660
ISSN: 0100-4042
Popis: Amino sugars are chemical compounds that have a sugar backbone, in which one of the hydroxyl groups is replaced by an amino group. Derivatives of amine-containing sugars, such as N-acetylglucosamine, are also considered amino sugars. The synthetic introduction of amino functionalities in a regio- and stereoselective manner ontosugar scaffolds represents a substantial challenge. Most of the modern methods for the preparation of 1-, 2- and 3-amino sugars are those starting from glycals, 2,3-unsaturated O-glycosides epoxy-sugars, keto-sugars among others. This review summarizes recente developments in the current state of knowledge concerning the occurrence, biosynthesis, synthesis and application of amino sugars.
Databáze: OpenAIRE