Cyto-Morphological Correlation of Indeterminate C3 (Atypical) and C4 (Suspicious) Categories in Fine Needle Aspiration Cytology of the Breast

Autor:	Bharti Rajni, Bansal Vikas Kumar, Sharma Priyam, Dixit Nutan
Rok vydání:	2021
Předmět:	Malignant Medicine (General) Pathology medicine.medical_specialty business.industry General Medicine Morphological correlation R5-920 Benign Fine needle aspiration cytology Fine-Needle aspiration cytology (FNAC) Histopathological correlation Medicine Indeterminate business
Zdroj:	Acta Medica Iranica, Vol 59, Iss 3 (2021)
ISSN:	1735-9694 0044-6025
DOI:	10.18502/acta.v59i3.5785
Popis:	In 1996, to harmonize the reporting system of breast lesions on fine-needle aspiration cytology (FNAC), National Cancer Institute (NCI) proposed five categories from C1-C5. C3 and C4 categories are noted to be ambiguous during histopathological correlation, hence “grey-zoned.” There have been limited researches regarding its usefulness and its histopathological correlation. This study was undertaken to evaluate C3 and C4 categories and to correlate with histopathological examination. This perspective and retrospective study was undertaken for two years. Forty cases of C3 and 32 cases of C4 were retrieved from a total of 602 cases of breast FNAC. Histopathological follow-up and correlation were available in 30 cases of C3 and 15 cases of category C4 and were selected for further study. On the histopathological correlation of the C3 category, 22 (73.3%) cases turned out to be benign, and 8 (26.7%) cases revealed malignant diagnosis, and among the C4 category, 2 (13.3%) cases revealed benign findings, and 13(86.7%) of the cases showed malignancy. This difference was statistically significant (P
Databáze:	OpenAIRE
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