Inhibition of protein kinase CK2 induces E2F1 nuclear export, formation of p21/E2F1 complexes and suppression of DNA synthesis in normal human epidermal keratinocytes
Autor: | V. Mitev, Antonia Isaeva |
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Rok vydání: | 2009 |
Předmět: |
Cyclin-Dependent Kinase Inhibitor p21
DNA Replication Keratinocytes Active Transport Cell Nucleus Down-Regulation Dermatology Biochemistry Proto-Oncogene Proteins c-myc P70S6 kinase Protein kinase CK2 E2F1 Humans Nuclear export signal CHUK Casein Kinase II Molecular Biology Protein Kinase Inhibitors Cells Cultured Cell Proliferation DNA synthesis Dose-Response Relationship Drug Chemistry Triazoles Epidermis E2F1 Transcription Factor Signal Transduction |
Zdroj: | Journal of dermatological science. 55(2) |
ISSN: | 1873-569X |
Databáze: | OpenAIRE |
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