Effectiveness of an oral diabetes-specific supplement on nutritional status, metabolic control, quality or life, and functional status in elderly patients. A multicentre study
| Autor: | Rebeca Sanz Barriuso, Jose Antonio Lopez Medina, Juan Ramon Domenech Pascual, Pilar Martín, Luis Lopez Penabad, Francisco José Tarazona Santabalbina, Francisco Robles Agudo, Alejandro Sanz París |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Activities of daily living Population Nutritional Status Critical Care and Intensive Care Medicine law.invention Dietary Fats Unsaturated Quality of life Randomized controlled trial law Internal medicine Diabetes mellitus Dietary Carbohydrates medicine Humans Prospective Studies education Aged Aged 80 and over education.field_of_study Nutrition and Dietetics business.industry Malnutrition medicine.disease Treatment Outcome Diabetes Mellitus Type 2 Dietary Supplements Quality of Life Patient Compliance Female Observational study business Body mass index |
| Zdroj: | Clinical Nutrition. 38:1253-1261 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/j.clnu.2018.05.007 |
| Popis: | Summary Background & aims The purpose of this study was to assess nutritional status, quality of life (QoL) and function in malnourished or at risk for malnutrition community-dwelling (CD) and nursing home-dwelling (NHD) elderly patients with type 2 diabetes mellitus (DM2), receiving treatment with a diabetes-specific oral nutritional supplement (DSONS). Methods A prospective, multicentre, observational study was conducted. A DSONS (high-calorie, high-protein, with slow-digestible carbohydrate and high monounsaturated fatty acid – MUFA-content – Glucerna® 1.5 Cal) had been prescribed the week before inclusion. The following assessments were undertaken at baseline (BL), at week 6 (V1) and at month 3 (FV): body mass index (BMI), glycosylated haemoglobin (HbA1c), nutritional status (Mini Nutritional Assessment – MNA), QoL (EQ-5D questionnaire), and functional status (Katz Index – KI of Independence in Activities of Daily Living). The data were reported in the overall population (OP) and in the CD and NHD groups. Results A total of 402 patients aged 80.8 ± 8.5 years were evaluable (44.5% men), including 61.7% CD and 38.3% NHD. BMI (kg/m2) increased in the OP from 22.0 ± 3.5 at BL to 22.5 ± 3.6 at V1 (p Conclusions In this study, conducted in routine, multicentre, clinical settings, the treatment with the high-calorie, high-protein, with slow-digestible carbohydrate, and high MUFA content DSNOS – Glucerna® 1.5 Cal-, was associated with improvements in HbA1c, nutritional status, BMI and QoL following 6 weeks and 3 months of treatment in both institutionalised and non-institutionalised elderly patients with diabetes who were malnourished or at risk for malnutrition. A slight improvement in functional status was also observed at 12 weeks. As this is an observational effectiveness study, a randomized controlled trial would be necessary to establish a causal relationship between the DSNOS and the described events. |
| Databáze: | OpenAIRE |
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