A clinical study of cutaneous leishmaniasis in a new focus in the Kurdistan region, Iraq

Autor: Abdulkareem M. Xedr, Zana Sidiq M. Saleem, Mohamed T. Zebary, Hindreen A. Aqrawi, Shiraz M. Hassan, Shivan S. Hafzullah, Amer A Balatay, Mahmood S. Hafzullah, Ramzy Sh. Sheikhan, Nawfal R Hussein, Mahde S. Assafi, Farasheen R. Amedi
Rok vydání: 2019
Předmět:
Male
Pathology and Laboratory Medicine
Treatment failure
Geographical Locations
Clinical study
030207 dermatology & venereal diseases
0302 clinical medicine
Zoonoses
Medicine and Health Sciences
Child
Leishmaniasis
Routes of Administration
Skin
Protozoans
Leishmania
Multidisciplinary
Eukaryota
Middle Aged
Infectious Diseases
Child
Preschool
Iraq
Medicine
Female
Skin lesion
Research Article
Neglected Tropical Diseases
Veterinary Medicine
Adult
medicine.medical_specialty
Asia
Adolescent
Science
030231 tropical medicine
Leishmaniasis
Cutaneous
Skin Diseases
Genus: Leishmania
Young Adult
03 medical and health sciences
Signs and Symptoms
Cutaneous leishmaniasis
Diagnostic Medicine
Protozoan infection
Internal medicine
Parasitic Diseases
medicine
Humans
Intramuscular Injections
Pharmacology
Protozoan Infections
business.industry
Organisms
Infant
Newborn
Biology and Life Sciences
Infant
Outbreak
Tropical Diseases
medicine.disease
Parasitic Protozoans
People and Places
Lesions
Veterinary Science
Livestock Care
business
Zdroj: PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0217683 (2019)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0217683
Popis: Leishmaniasis is caused by protozoan parasites of the genus Leishmania and is a major health problem in various parts of the world. Cutaneous leishmaniasis (CL) occurs, among others, in unpredictable outbreaks after wars and disasters. After the last war in Iraq, the collapse of the health system led to the spread of infectious diseases, including CL. Between September 2016 and November 2017, all patients with confirmed CL having one or more skin lesion(s) were referred to a regional health center in Musol City within the Rabeea District. During this period, 1539 patients visited the clinic. A total of 190 patients were excluded from the study because of poor follow-up. The treatment success rate was 97.7% (1319/1349). Statistically significant associations were found between number of lesions and treatment failure (p = 0.0018; OR = 1.4430; CI = 1.1466-1.8161), number of doses and number of lesions (Pearson's correlation coefficient = 0.095; p = 0.001), and the lack of municipality services and number of doses used for the treatment (p = 0.008; OR = 1.0629; CI = 1.0158-1.1122). To conclude, the highest number of patients with CL in the city of Musol was recorded after the war in Iraq. The treatment success rate was high, which reflected the strict treatment and follow-up program. An urgent plan is needed to stop the spread of infection.
Databáze: OpenAIRE
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