A Simple, Reliable Method for the Determination of Chlorinated Volatile Organics in Human Breath and Air Using Glass Sampling Tubes
| Autor: | Rajinder S. Narang, Vincent B. Stein, Kenneth M. Aldous, Lloyd R. Wilson |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Chromatography
Gas Health Toxicology and Mutagenesis Safety shutoff valve Toxicology Specimen Handling Analytical Chemistry chemistry.chemical_compound Swimming Pools Natural rubber Humans Environmental Chemistry Trichloroethanes Tube (fluid conveyance) Carbon Tetrachloride Detection limit Air Pollutants Chemical Health and Safety Chloroform Chromatography Reproducibility of Results Reference Standards Breath Tests chemistry Air Pollution Indoor visual_art Solvents visual_art.visual_art_medium Carbon tetrachloride Glass Gas chromatography Volatilization Trichloroethane |
| Zdroj: | Journal of Analytical Toxicology. 20:145-150 |
| ISSN: | 1945-2403 0146-4760 |
| Popis: | [Abstract A method for determining chloroform, 1,1,1 -trichloroethane, carbon tetrachloride, and trichloroethene in breath samples was developed. It consisted of collecting samples in 40-mL glasssilanized tubes that were 16-in. long and had a 0.64-in. diameter. The ends tapered, resulting in a tube with a 1/4-in. diameter that was 13/4-in. long; each end had a shutoff valve attached. One end had a strip of rubber tube attached to the shutoff valve for collecting the breath sample, and the other end contained a 1/4-in. Swagelok nut with a rubber septum for withdrawing the sample. Samples were withdrawn using a pressure-lock, gaslight syringe, and they were injected onto a gas chromatograph fitted with an electron-capture detector. The analyles were stable for at least 22 days in these tubes. The method detection limit was determined to be 0.03, 0.08, 0.04, and 0.04 pg/mt for chloroform, 1,1,1-trichloroethane, carbon tetrachloride, and trichloroethene, respectively. Precision, based on 13 injections, was determined to be 13% for 0.09 pg chloroform, 13% for 0.21 pg 1,1,1trichloroethane, 8% for 0.16 pg carbon tetrachloride, and 14% for 0.1 pg trichloroethene. In all, the proposed method is a sensitive and reliable one for determining volatile organic compounds in breath and a method that can also be applied to air sampling. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|