Isolation of male embryonal carcinoma cells and their chromosome replication patterns
| Autor: | Michael W. McBurney, Brenda J. Rogers |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
DNA Replication
Male Somatic cell Biology Y chromosome Cell Line Embryonal carcinoma Mice Y Chromosome medicine Animals Interphase Molecular Biology S phase Mice Inbred C3H Sex Chromosomes Teratoma Karyotype Embryo Cell Biology medicine.disease Molecular biology Transplantation Bromodeoxyuridine Cell culture Karyotyping embryonic structures Developmental Biology |
| Zdroj: | Developmental Biology. 89:503-508 |
| ISSN: | 0012-1606 |
| DOI: | 10.1016/0012-1606(82)90338-4 |
| Popis: | We have induced teratocarcinomas in C3H He strain mice by extra-uterine transplantation of egg cylinder stage embryos. Embryonal carcinoma cell lines with male karyotypes were isolated from three different tumor lines. One of the cell lines has a normal karyotype. The Y chromosome in each of two lines tested replicates late during the S phase of the cell cycle at the same time as Y chromosomes in male somatic cells. |
| Databáze: | OpenAIRE |
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