Multiple Cutaneous Angiosarcomas after Breast Conserving Surgery and Bilateral Adjuvant Radiotherapy: An Unusual Case and Review of the Literature
| Autor: | Carla De Luca Cardillo, Icro Meattini, Donato Casella, Lorenzo Orzalesi, Raffaella Santi, R. Simoncini, Milena Paglierani, Jacopo Nori, I. Giacomelli, Daniele Scartoni, Lorenzo Livi, Vieri Scotti |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Adjuvant radiotherapy Unusual case business.industry medicine.medical_treatment Secondary cancer cutaneous angiosarcomas adjuvant radiotherapy Case Report medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Bilateral breast cancer lcsh:RC254-282 Resection Surgery Radiation therapy Radiation exposure Breast cancer Oncology medicine Breast-conserving surgery Radiology business |
| Zdroj: | Case Reports in Oncological Medicine, Vol 2014 (2014) Case Reports in Oncological Medicine |
| ISSN: | 2090-6714 2090-6706 |
| Popis: | Breast angiosarcomas (BAs) are rare but serious events that may arise after radiation exposure. Disease outcome is poor, with high risk of local and distant failure. Recurrences are frequent also after resection with negative margins. The spectrum of vascular proliferations associated with radiotherapy in the setting of breast cancer has expanded, including radiation-associated atypical vascular lesions (AVLs) of the breast skin as a rare, but well-recognized, entity. Although pursuing a benign behavior, AVLs have been regarded as possible precursors of postradiation BAs. We report an unusual case of a 71-year-old woman affected by well-differentiated bilateral cutaneous BA, diagnosed 1.9 years after adjuvant RT for synchronous bilateral breast cancer. Whole-life clinical followup is of crucial importance in breast cancer patients. |
| Databáze: | OpenAIRE |
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