Risk factors associated with cardiovascular morbidity and mortality in Spanish incident hemodialysis patients: two-year results from the ANSWER study
| Autor: | Fernando García, Javier Lozano, Joan Fort, Alejandro Martin-Malo, Xavier de las Cuevas, Fina Lladós, Rafael Pérez-García |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Catheters medicine.medical_treatment Disease Body Mass Index Renal Dialysis Risk Factors medicine Humans Prospective Studies Intensive care medicine Serum Albumin Proportional Hazards Models business.industry Hematology General Medicine Catheter Nephrology Cardiovascular Diseases Spain Emergency medicine Ferritins Kidney Failure Chronic Observational study Female Hemodialysis business Body mass index |
| Zdroj: | Blood purification. 33(1-3) |
| ISSN: | 1421-9735 |
| Popis: | Aims: To identify factors associated with cardiovascular (CV) disease in hemodialysis. Methods: Multicenter, prospective, 2-year, observational study in 2,310 incident patients (3,496 patient-years). Multivariate Cox models determined baseline characteristics associated with CV disease. Results: Main factors associated with CV deaths (6.3/100 patient-years) were: high Charlson score (hazard ratio (HR) 3.6; 95% confidence interval (CI) 1.7–7.5 for ≧9 vs. ≤4); low Karnofsky score (KS; HR 2.2; 95% CI 1.5–3.3 for KS ≤50 vs. >70); female gender (HR 1.4; 95% CI 1.1–1.9); catheter access (HR 1.4; 95% CI 1.0–1.9); low (Conclusions: There is a high CV risk, especially in older patients with high comorbidity, low BMI, low albumin or iron deficiency. Catheter access increases the CV death risk. |
| Databáze: | OpenAIRE |
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