Aetiology of neonatal conjunctivitis evaluated in a population‐based setting
| Autor: | Marjo Renko, Terhi Tapiainen, Matti Uhari, Irma Ikäheimo, Tytti Pokka, Minna Honkila |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Microbiological culture Population Viral Conjunctivitis Chlamydia trachomatis medicine.disease_cause Neonatal conjunctivitis 03 medical and health sciences 0302 clinical medicine Internal medicine Streptococcus pneumoniae medicine Humans 030212 general & internal medicine Prospective Studies Aetiology education Bacterial Conjunctivitis education.field_of_study Respiratory viruses business.industry Infant Newborn Regular Article General Medicine medicine.disease Conjunctivitis Neisseria gonorrhoeae Pediatrics Perinatology and Child Health 030221 ophthalmology & optometry Neonatology business Regular Articles |
| Zdroj: | Acta Paediatrica (Oslo, Norway : 1992) |
| ISSN: | 1651-2227 0803-5253 |
| Popis: | Aim Our aim was to study prospectively the aetiology of neonatal conjunctivitis in a population‐based setting. Methods Altogether 173 neonates with clinical conjunctivitis aged on average 20 (SD 10) days were recruited from child welfare clinics in Oulu, Finland, in 2010–2015. Conjunctival specimens were collected from 167 neonates for multiplex polymerase chain reaction to detect 16 respiratory viruses, from 163 for polymerase chain reaction to detect Chlamydia trachomatis and Neisseria gonorrhoeae and from 160 for bacterial culture studies. The cases were followed up until the age of 18 months. Results Viral conjunctivitis was diagnosed in 8/167 (4.8%; 95% CI 2.1–9.2%), chlamydial or gonococcal conjunctivitis in 0/163 cases (0%; 95% CI 0–2.2%) and other bacterial conjunctivitis in 58/160 (36%; 95% CI 29–44%). Rhinovirus was found at the ocular site in 4/167 (2.4%) neonates, adenovirus in 3/167 (1.8%) and bocavirus in 1/167 (0.6%). The most commonly isolated bacteria included Staphylococcus aureus (16%), Moraxella catarrhalis (9.4%) and Streptococcus pneumoniae (3.1%). None of these pathogens was associated with the 4/173 (2.3%) cases later operated on for persistent nasolacrimal duct obstruction. Conclusion Chlamydia trachomatis was a rare pathogen in neonatal conjunctivitis in a population‐based setting, but respiratory viruses were detected more frequently than indicated earlier. |
| Databáze: | OpenAIRE |
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