A comparison of the universal TOR Guideline to the absence of prehospital ROSC and duration of resuscitation in predicting futility from out-of-hospital cardiac arrest
| Autor: | Paul R. Leslie, Ian R. Drennan, Yan Xiong, Mark Charleston, Robert H. Schmicker, Michael Austin, Laurie J. Morrison, Jamie Jasti, Joshua C. Reynolds, P. Richard Verbeek, Ahamed H. Idris, Heather Herren, Erin Case, Zachary D. Goldberger |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Emergency Medical Services medicine.medical_specialty Resuscitation medicine.medical_treatment 030204 cardiovascular system & hematology Emergency Nursing Return of spontaneous circulation Article Out of hospital cardiac arrest 03 medical and health sciences 0302 clinical medicine medicine Emergency medical services Humans Cardiopulmonary resuscitation Intensive care medicine Aged Retrospective Studies business.industry 030208 emergency & critical care medicine Guideline Middle Aged Cardiopulmonary Resuscitation Practice Guidelines as Topic Emergency Medicine Etiology Female Cardiology and Cardiovascular Medicine business Out-of-Hospital Cardiac Arrest Cohort study |
| Zdroj: | Resuscitation. 111:96-102 |
| ISSN: | 0300-9572 |
| Popis: | Introduction The Universal Termination of Resuscitation (TOR) Guideline accurately identifies potential out-of-hospital cardiac arrest (OHCA) survivors. However, implementation is inconsistent with some Emergency Medical Service (EMS) agencies using absence of return of spontaneous circulation (ROSC) as sole criterion for termination. Objective To compare the performance of the Universal TOR Guideline with the single criterion of no prehospital ROSC. Second, to determine factors associated with survival for patients transported without a ROSC. Lastly, to compare the impact of time to ROSC as a marker of futility to the Universal TOR Guideline. Design Retrospective, observational cohort study. Participants Non-traumatic, adult (≥18 years) OHCA patients of presumed cardiac etiology treated by EMS providers. Setting ROC-PRIMED and ROC-Epistry post ROC-PRIMED databases between 2007 and 2011. Outcomes Primary outcome was survival to hospital discharge and the secondary outcome was functional survival. We used multivariable regression to evaluate factors associated with survival in patients transported without a ROSC. Results 36,543 treated OHCAs occurred of which 9467 (26%) were transported to hospital without a ROSC. Patients transported without a ROSC who met the Universal TOR Guideline for transport had a survival of 3.0% (95% CI 2.5–3.4%) compared to 0.7% (95% CI 0.4–0.9%) in patients who met the Universal TOR Guideline for termination. The Universal TOR Guideline identified 99% of survivors requiring continued resuscitation and transportation to hospital including early identification of survivors who sustained a ROSC after extended durations of CPR. Conclusion Using absence of ROSC as a sole predictor of futility misses potential survivors. The Universal TOR Guideline remains a strong predictor of survival. |
| Databáze: | OpenAIRE |
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