LED-generated Multifocal ERG On- and Off-responses in Complete Congenital Stationary Night Blindness - A Case Report
| Autor: | Anja M. Palmowski-Wolfe, Chrisitan Prünte, Dorothee Leifert, Margarita G. Todorova |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Multifocal ERG Eye disease Complete type Dark Adaptation Severity of Illness Index Retina Vision disorder Night Blindness Physiology (medical) Ophthalmology Electroretinography medicine Humans Congenital stationary night blindness medicine.diagnostic_test business.industry Middle Aged medicine.disease Sensory Systems Surgery Female Complete congenital stationary night blindness medicine.symptom business Erg Photic Stimulation |
| Popis: | We report on the application of a light emitting diode (LED) screen to elicit multifocal ERG on- and off-responses in a patient presenting with the complete type of congenital stationary night blindness (cCSNB): A 63-years old woman was diagnosed with cCSNB by means of standard ERG procedures and dark adaptometry. To confirm this diagnosis and to investigate topographical differences of on- and off-responses a multifocal approach employing long-duration stimuli was added. Results of mfERG-testing were averaged in three groups (a central area of 7.5 degrees , a ring area of 7.5-21.9 degrees and a peripheral ring of 21.9-31.1 degrees ). When compared to normal controls (n = 4) on-responses (P1-amplitudes) were severely reduced symmetrically at all eccentricities, while off-responses showed no reduction resulting in an increased off/on-ratio. Furthermore on-latencies of P1 were delayed symmetrically at all eccentricities, whereas off-latencies were normal. To our knowledge this is the first report of multifocal on- and off-responses in a CSNB-patient. Stimulus-generation with a LED-screen provides the advantage of a stable luminance during the long-duration on-phase. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|