51Cr-bleomycin in the diagnosis of tumours of the chest
| Autor: | S. Fajndt, Mussur M, Durski K, Dobek J, Brykalski D, J. Liniecki, T. Pertynski, M Studniarek |
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| Předmět: |
Adult
Thorax medicine.medical_specialty Adolescent Scintigraphy Bleomycin law.invention chemistry.chemical_compound law Humans Medicine Radiology Nuclear Medicine and imaging Child Radionuclide Imaging Aged Gamma camera Lung medicine.diagnostic_test business.industry Respiratory disease General Medicine Middle Aged Thoracic Neoplasms medicine.disease Chromium Radioisotopes Radiography medicine.anatomical_structure chemistry Evaluation Studies as Topic Child Preschool Lymphatic Metastasis Radiology Decision threshold business Nuclear medicine |
| Zdroj: | Europe PubMed Central |
| Popis: | Summary 51Cr-bleomycin was used for the scintigraphic diagnosis of primary and secondary tumours of the thorax. The study was based on observations in 104 patients. The scintigraphy was performed using a gamma camera coupled to an on-line computer. Active lesions were scored using a semiquantitative scale of scores 0 to 5. Images were subdivided into 222 regions considered. In 72 of these, the presence of disease was diagnosed (64 malignant, 8 non-malignant) and 150 regions were classified as free from disease. At the decision threshold of score 2, over-all sensitivity and specificity of the scintigraphic detection of malignant tumours amounted to 97 and 79%, respectively. Inflammatory changes displayed some detectable accumulation of 51Cr-bleomycin but scores attributed to these lesions did not exceed the value of 2. |
| Databáze: | OpenAIRE |
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