Effects of large-volume paracentesis on pulmonary function in patients with tense cirrhotic ascites
| Autor: | Shailesh C. Kadakia, Carlos E. Angueira |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
Vital capacity medicine.medical_specialty Cirrhosis Punctures Suction Gastroenterology Pulmonary function testing Functional residual capacity Liver Cirrhosis Alcoholic Internal medicine Ascites Paracentesis medicine Humans Lung volumes Prospective Studies Respiratory system Lung Hepatology medicine.diagnostic_test business.industry medicine.disease Respiratory Function Tests Female medicine.symptom business |
| Zdroj: | Hepatology. 20:825-828 |
| ISSN: | 1527-3350 0270-9139 |
| DOI: | 10.1002/hep.1840200409 |
| Popis: | Large-volume paracentesis is an accepted therapeutic modality for the treatment of tense ascites in patients with cirrhosis. Whereas the effects of large-volume paracentesis on the cardiovascular system have been studied in great detail, the effects of tense ascites and large-volume paracentesis on the respiratory system have undergone only limited evaluation. Most patients report symptomatic improvement in breathing after large-volume paracentesis. The aim of our study was to prospectively evaluate the effects of large-volume paracentesis on the pulmonary function of patients with tense ascites. Nine patients with alcoholic cirrhosis and tense ascites underwent large-volume paracentesis (mean, 3,500 ml of ascites removed) followed by intravenous albumin infusion (10 gm/L ascites removed). Pulmonary function tests were performed just before and 2 hr after large-volume paracentesis. The functional residual capacity increased from 2.46 +/- 0.92 to 2.99 +/- 0.97 L (p = 0.01) and total lung capacity from 5.08 +/- 1.18 to 5.72 +/- 1.32 L (p = 0.03). The forced vital capacity, expiratory reserve volume and residual volume also increased but were not statistically significant (p = 0.07 for all). We noted no significant improvement in forced expiratory volume in 1 sec, forced expiratory effort 25% to 75%, vital capacity or diffusion capacity. There was marked symptomatic improvement in all patients. We conclude that large-volume paracentesis improves measured lung volumes within hours in patients with tense ascites. |
| Databáze: | OpenAIRE |
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