Risk factors for disease progression in COVID-19 patients
| Autor: | Yu Kyung Park, Min Cheol Chang, Bong Ok Kim, Donghwi Park |
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| Rok vydání: | 2020 |
| Předmět: |
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medicine.medical_specialty Fever Pneumonia Viral Disease Asymptomatic lcsh:Infectious and parasitic diseases Cohort Studies Diabetes Complications Betacoronavirus 03 medical and health sciences 0302 clinical medicine Risk Factors Diabetes mellitus Internal medicine Republic of Korea Odds Ratio Humans Medicine lcsh:RC109-216 030212 general & internal medicine Pandemics Chilling Retrospective Studies Risk factor: symptom aggravation SARS-CoV-2 business.industry Diabetes COVID-19 Retrospective cohort study Odds ratio Middle Aged medicine.disease Coronavirus disease Pneumonia Logistic Models Infectious Diseases 030220 oncology & carcinogenesis Multivariate Analysis Disease Progression Female Chills medicine.symptom Coronavirus Infections business Research Article Cohort study |
| Zdroj: | BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-6 (2020) BMC Infectious Diseases |
| ISSN: | 1471-2334 |
| Popis: | Background Coronavirus disease (COVID-19) is rapidly spreading worldwide. Although 10–20% of patients with COVID-19 have severe symptoms, little is known about the risk factors related to the aggravation of COVID-19 symptoms from asymptomatic or mild to severe disease states. Methods This retrospective study included 211 patients who were asymptomatic or with mild presentations of COVID-19. We evaluated the differences in demographic and clinical data between the cured (discharged to home) and transferred (aggravated to severe-stage COVID-19) groups. Results A multivariate logistic analysis showed that body temperature, chills, initial chest X-ray findings, and the presence of diabetes were significantly associated with predicting the progression to severe stage of COVID-19 (p Conclusions Even if patients are asymptomatic or have mild symptoms, clinicians should closely observe patients with COVID-19 presenting with chills, body temperature > 37.5 °C, findings of pneumonia in chest X-ray, or diabetes. |
| Databáze: | OpenAIRE |
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