Clinical Efficacy of Immune Checkpoint Inhibitors in Older Non-small-Cell Lung Cancer Patients: A Meta-Analysis

Autor:	Ying Wang, Xin-Xing Sun, Zhi-Ping Gong, You-Meng Sun, Jing Chen, Hai-Yan Meng
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	0301 basic medicine Oncology medicine.medical_specialty Cancer Research medicine.medical_treatment Immune checkpoint inhibitors chemotherapy PD-1/PD-L1 lcsh:RC254-282 law.invention immune checkpoint inhibitors 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Older patients non-small- cell lung cancer law Internal medicine medicine Clinical efficacy Lung cancer Chemotherapy business.industry medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens meta-analysis 030104 developmental biology 030220 oncology & carcinogenesis Meta-analysis Systematic Review Non small cell business
Zdroj:	Frontiers in Oncology, Vol 10 (2020) Frontiers in Oncology
DOI:	10.3389/fonc.2020.558454/full
Popis:	Background: Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape among non-small-cell lung cancer (NSCLC) patients. The efficacy of ICI therapy in older patients (≥65 years) is controversial and not fully clarified. We performed a systematic review and meta-analysis to evaluate the efficacy of ICIs in patients with advanced or metastatic NSCLC based on age (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45c0a88d1c9cc1ce0e6cbf50e44e441 https://www.frontiersin.org/article/10.3389/fonc.2020.558454/full Zobrazit plný text záznamu