MOESM2 of Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis

Autor: Schrewe, Lisa Thiele Née, Guse, Kirsten, Tietz, Silvia, Remlinger, Jana, Demir, Seray, Pedreiturria, Xiomara, Hoepner, Robert, Salmen, Anke, Pistor, Maximilian, Turner, Timothy, Engelhardt, Britta, Hermann, Dirk, Lühder, Fred, Wiese, Stefan, Chan, Andrew
Rok vydání: 2020
DOI: 10.6084/m9.figshare.11557959
Popis: Additional file 2: Figure S2. Differential abcg2-expression during experimental autoimmune encephalomyelitis. Relative abcg2-mRNA (quantification by TaqMan PCR using ΔΔct method; normalized to ß-actin) during the acute or chronic phase of MOG35-55 EAE in female C57BL/6 J wild type mice compared to healthy controls. (A) spinal cord, Kruskal-Wallis test; (B) liver, MWU-test; (C) splenic T cells, Kruskal-Wallis test; (D) spleen, MWU-test. Ctrl: healthy control; ac EAE: acute phase of EAE (d16/18 after immunization); chr EAE: chronic phase of EAE (d26 after immunization); statistics: *p
Databáze: OpenAIRE