Distinction between porcine circovirus type 2 enteritis and porcine proliferative enteropathy caused by Lawsonia intracellularis
| Autor: | Birgitta Svensmark, Håkan Vigre, Vivi Bille-Hansen, Tim Kåre Jensen |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Circovirus
Pathology medicine.medical_specialty Swine animal diseases Lawsonia Bacteria Ileum Pathology and Forensic Medicine Enteritis Lawsonia intracellularis Microbiology Diagnosis Differential medicine Animals Ileitis Circoviridae Infections Swine Diseases Lamina propria General Veterinary biology business.industry virus diseases medicine.disease biology.organism_classification Porcine circovirus Desulfovibrionaceae Infections medicine.anatomical_structure business |
| Zdroj: | Journal of comparative pathology. 135(4) |
| ISSN: | 0021-9975 |
| Popis: | The presence of porcine circovirus type 2 (PCV2) was studied immunohistochemically in formalin-fixed, paraffin wax-embedded samples of intestinal tissue from 80 pigs with a clinical history suggestive of Lawsonia intracellularis-associated diarrhoea. Histopathologically, enteritis of varying intensity was diagnosed in 64 of the pigs. Of these 64 animals, 34 (18%) were infected with both PCV2 and L. intracellularis. Of the remaining 30 cases of enteritis, 23 (77%) were attributed to PCV2 infection alone. The PCV2-associated enteritis cases showed necrotizing ileitis and colitis, indistinguishable macroscopically from proliferative enteritis (PE) due to L. intracellularis. Histopathologically, L. intracellularis-positive intestines showed adenomatous proliferation of crypt enterocytes, whereas PCV2 enteritis was characterized by histiocytosis of varying intensity, with PCV2-positive cells in the submucosa, lamina propria and crypt epithelium, as well as in the lymphoid tissue of the ileum and colon. Multinucleated giant cells, however, were seen in both infections. PCV2 was about three times more likely to be detected in L. intracellularis-negative than in L. intracellularis-positive samples (P |
| Databáze: | OpenAIRE |
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