Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review
| Autor: | Maryam Dadar, Ryhaneh Babaei, Bahman Mirzaei, Habib Zeighami, Ali Soltani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Staphylococcus aureus biology staphylococcal infections Staphylococcus aureus business.industry Immunogenicity Mini Review Virulence immunoprophylaxis biology.organism_classification Antimicrobial medicine.disease_cause Microbiology QR1-502 Mini review Healthcare settings medicine prophylaxis candidate vaccines business Staphylococcus Bacteria |
| Zdroj: | Frontiers in Microbiology Frontiers in Microbiology, Vol 12 (2021) |
| ISSN: | 1664-302X |
| Popis: | Since the 1960s, the frequency of methicillin-resistant Staphylococcus aureus as a recurrent cause of nosocomial infections has increased. Since multidrug-resistant Staphylococcus has overcome antimicrobial treatment, the development of putative vaccines based on virulence factors could be a great help in controlling the infections caused by bacteria and are actively being pursued in healthcare settings. This mini-review provides an overview of the recent progress in vaccine development, immunogenicity, and therapeutic features of some S. aureus macromolecules as putative vaccine candidates and their implications against human S. aureus-related infections. Based on the reviewed experiments, multivalent vaccines could prevent the promotion of the diseases caused by this bacterium and enhance the prevention chance of S. aureus infections. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|