Can the evolution of male contraception lead to a revolution? Review of the current state of knowledge
| Autor: | Marcin Matuszewski, Mikołaj Frankiewicz, Wojciech Połom |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Review Paper
reversible inhibition of sperm under guidance medicine.medical_specialty male contraception 030219 obstetrics & reproductive medicine vasectomy business.industry Periodic Abstinence 030232 urology & nephrology Vasectomy Testosterone (patch) Male contraceptive General Medicine 03 medical and health sciences 0302 clinical medicine Hormonal contraception Male fertility Family planning Family medicine testosterone Reversible inhibition of sperm under guidance Medicine business |
| Zdroj: | Central European Journal of Urology |
| ISSN: | 2080-4873 |
| DOI: | 10.5173/ceju.2017.1450 |
| Popis: | Introduction Great advances in medical research concerning methods of contraception have been achieved in recent years, however, more than 25% of couples worldwide still rely on condoms - a method with poor efficacy. Even though there is a spectrum of 11 different contraceptive methods for women, there are only 4 commonly used by men (condoms, periodic abstinence, withdrawal and vasectomy). In this review, advances and present, state-of-the-art, both hormonal and non-hormonal male contraceptive methods will be presented and evaluated. Potential novel targets that warrant greater research will be highlighted. Material and methods A comprehensive literature search without a time limit was performed using the Medline database on May 2017. The terms 'male contraception' in conjunction with 'reversible inhibition of sperm under guidance' (RISUG), 'hormonal', 'non-hormonal', 'vasectomy' or 'testosterone' were used. The articles were limited to those published in English, Polish or French. Results There are various contraceptives currently available to regulate male fertility. Vasectomy is still the most effective permanent form of male contraceptive with a failure rate lower than 1%. Reversible, non hormonal methods of male contraception, like reversible inhibition of sperm under guidance, are very promising and close to being introduced into the market. In regards to hormonal contraception research, the use of testosterone injections has been widely studied yet they often harbor undesirable side effects and require further development. Conclusions Despite continuous efforts worldwide, it seems that another several years of research is needed to provide safe, effective and affordable male contraceptives which will allow both men and women to participate fully in family planning. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|