Factors associated with adherence to ursodeoxycholic acid or placebo in patients after bariatric surgery

Autor: Maimoena S.S. Guman, Sylke Haal, L. Maurits de Brauw, Barbara A. Hutten, Prof Max Nieuwdorp, Bastiaan Nuijen, Ruben Schouten, Ruben N. van Veen, Prof Marcel G.W. Dijkgraaf, Rogier P. Voermans, Victor E.A. Gerdes
Přispěvatelé: Gastroenterology and hepatology, Internal medicine, Graduate School, Vascular Medicine, Gastroenterology and Hepatology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Epidemiology and Data Science, ACS - Diabetes & metabolism, APH - Aging & Later Life, APH - Health Behaviors & Chronic Diseases, Experimental Vascular Medicine, APH - Methodology
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Surgery for Obesity and Related Diseases, 18(6), 755-761. Elsevier Inc.
Surgery for obesity and related diseases, 18(6), 755-761. Elsevier Inc.
ISSN: 1550-7289
Popis: Background: Ursodeoxycholic acid (UDCA) reduces symptomatic gallstone disease after Roux-en-Y gastric bypass (RYGB). The beneficial effect of UDCA is reduced by poor adherence. Objectives: We aimed to identify factors associated with poor adherence to UDCA or placebo after bariatric surgery. Setting: Outpatient clinic and department for bariatric surgery in three hospitals in the Netherlands. Methods: Patients in the multicenter, double-blind, randomized, placebo-controlled UPGRADE trial were assessed for adherence to 900 mg UDCA or placebo for 6 months through a pill count, inquiries during follow-up, and a questionnaire. Poor adherence was defined as the usage of
Databáze: OpenAIRE