The role of quantitation in clinical nuclear cardiology: The University of Virginia approach
| Autor: | William H. Smith, Denny D. Watson |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Diagnostic Imaging
Male medicine.medical_specialty Cardiology Diastole Ischemia Ventricular Function Left Muscle hypertrophy Internal medicine Image Processing Computer-Assisted Humans Medicine Radiology Nuclear Medicine and imaging Myopathy Tomography Emission-Computed Single-Photon Academic Medical Centers Electronic Data Processing Ejection fraction business.industry Myocardium Virginia Coronary flow reserve medicine.disease Perfusion Volume measurements ROC Curve Female medicine.symptom Cardiology and Cardiovascular Medicine business Software |
| Zdroj: | Journal of Nuclear Cardiology. 14:466-482 |
| ISSN: | 1071-3581 |
| DOI: | 10.1016/j.nuclcard.2007.06.007 |
| Popis: | Measurement of regional myocardial tracer concentration after stress and at rest allows the establishment of normal standards for myocardial perfusion and reversibility and provides a reference from which to determine disease severity and change in response to treatment. Using the partial-volume effect, we can also conveniently estimate regional myocardial thickening fractions corresponding to the same segments used for perfusion quantitation. This adds close comparison of perfusion and function as an aid to viability assessment and for recognition of possible ischemic dysfunction in cases of balanced ischemia or globally exhausted coronary flow reserve. Volume measurements are added to routinely determine body surface area-normalized end-systolic and end-diastolic volume indices. Left ventricular ejection fraction is estimated from both volume measurements and from regional thickening fractions. Reduced regional thickening fractions and elevated end-systolic volume index are early indicators of myopathy, and these measurements may add significant information to the traditional perfusion study, particularly in cases of hypertrophy and diastolic dysfunction. |
| Databáze: | OpenAIRE |
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