Correlation between NT proBNP and left ventricular ejection fraction in elderly patients presenting to emergency department with dyspnoea
| Autor: | Amulya C. Belagavi, Aslam Y. Pillai, Medha Y Rao, U.S. Srihari |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system medicine.drug_class Population lcsh:Surgery Shortness of breath Cohort Studies Ventricular Dysfunction Left Internal medicine Natriuretic Peptide Brain medicine Natriuretic peptide Humans cardiovascular diseases education Medical attention Aged Aged 80 and over education.field_of_study Ejection fraction business.industry Age Factors Stroke Volume Stroke volume Emergency department lcsh:RD1-811 Middle Aged humanities Peptide Fragments Dyspnea Echocardiography lcsh:RC666-701 LV dysfunction Cardiology Biomarker (medicine) NT proBNP Original Article Female Cardiology and Cardiovascular Medicine business Emergency Service Hospital hormones hormone substitutes and hormone antagonists Biomarkers Cohort study |
| Zdroj: | Indian Heart Journal, Vol 64, Iss 3, Pp 302-304 (2012) |
| Popis: | Objective: Shortness of breath is a common complaint for which the elderly seek medical attention in the emergency department (ED). Differentiating cardiac from respiratory causes of dyspnoea in this population is quite a challenge. N Terminal pro brain-natriuretic-peptide (NT proBNP) has been studied extensively as a biomarker of left ventricular (LV) failure. Methods: The NT proBNP was measured in 100 patients above 60 years of age who presented to the ED with shortness of breath. The level was compared with echocardiographic findings to assess correlation with ejection fraction (EF). Results: The NT proBNP values increased significantly as the functional severity of heart failure (HF) increased (P < 0.001). The mean NT proBNP level was 1503.33 pg/mL. Patients with respiratory causes of dyspnoea had a mean NT proBNP level of 309.28 pg/mL with normal LV function. Conclusion: The NT proBNP levels had a good correlation with worsening LVEF. |
| Databáze: | OpenAIRE |
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