Molecular networks of insulin signaling and amino acid metabolism in subcutaneous adipose tissue are altered by body condition in periparturient Holstein cows

Autor: Chuang Xu, Yusheng Liang, Ahmed A. Elolimy, Erminio Trevisi, V. Lopreiato, Abdulrahman S. Alharthi, Juan J. Loor, Carlos Fernández, I. Martinez-Cortés, R. Bucktrout
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adipose tissue
PRODUCCION ANIMAL
amino acid transporter
chemistry.chemical_compound
Pregnancy
Adipocyte
Lactation
insulin resistance
Insulin
Urea cycle
Amino Acids
chemistry.chemical_classification
0303 health sciences
Body condition
Chemistry
Amino acid transporter
Postpartum Period
Settore AGR/19 - ZOOTECNICA SPECIALE
04 agricultural and veterinary sciences
medicine.anatomical_structure
Female
body condition
Signal Transduction
medicine.medical_specialty
subcutaneous adipose tissue
Subcutaneous adipose tissue
Nitrogen
Subcutaneous Fat
Total mixed ration
03 medical and health sciences
Insulin resistance
Internal medicine
Genetics
medicine
urea cycle
Animals
030304 developmental biology
Retrospective Studies
0402 animal and dairy science
Glucose transporter
Parturition
Fatty acid
Metabolism
medicine.disease
040201 dairy & animal science
Diet
Endocrinology
Body Constitution
Animal Science and Zoology
Cattle
Energy Metabolism
Biomarkers
Food Science
Zdroj: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Popis: [EN] Peripartal cows mobilize not only body fat but also body protein to satisfy their energy requirements. The objective of this study was to determine the effect of prepartum BCS on blood biomarkers related to energy and nitrogen metabolism, and mRNA and protein abundance associated with AA metabolism and insulin signaling in subcutaneous adipose tissue (SAT) in peripartal cows. Twenty-two multiparous Holstein cows were retrospectively classified into a high BCS (HBCS; n = 11, BCS >= 3.5) or normal BCS (NBCS; n = 11, BCS
Y. Liang is a recipient of a doctoral fellowship from the China Scholarship Council (CSC, Beijing, China) to perform his PhD studies at the University of Illinois (Urbana). A. S. Alharthi received a fellowship from King Saud University (Riyadh, Saudi Arabia) to perform his PhD studies at the University of Illinois (Urbana). A. A. Elolimy was recipient of a fellowship from the Higher Education Ministry (Cairo, Egypt) to perform his PhD studies at the University of Illinois (Urbana). We thank Perdue AgriBusiness (Salisbury, MD) for the donation of ProvAAL2 AADvantage during the course of the experiment. The authors declare no conflicts of interest.
Databáze: OpenAIRE