Molecular networks of insulin signaling and amino acid metabolism in subcutaneous adipose tissue are altered by body condition in periparturient Holstein cows
Autor: | Chuang Xu, Yusheng Liang, Ahmed A. Elolimy, Erminio Trevisi, V. Lopreiato, Abdulrahman S. Alharthi, Juan J. Loor, Carlos Fernández, I. Martinez-Cortés, R. Bucktrout |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adipose tissue
PRODUCCION ANIMAL amino acid transporter chemistry.chemical_compound Pregnancy Adipocyte Lactation insulin resistance Insulin Urea cycle Amino Acids chemistry.chemical_classification 0303 health sciences Body condition Chemistry Amino acid transporter Postpartum Period Settore AGR/19 - ZOOTECNICA SPECIALE 04 agricultural and veterinary sciences medicine.anatomical_structure Female body condition Signal Transduction medicine.medical_specialty subcutaneous adipose tissue Subcutaneous adipose tissue Nitrogen Subcutaneous Fat Total mixed ration 03 medical and health sciences Insulin resistance Internal medicine Genetics medicine urea cycle Animals 030304 developmental biology Retrospective Studies 0402 animal and dairy science Glucose transporter Parturition Fatty acid Metabolism medicine.disease 040201 dairy & animal science Diet Endocrinology Body Constitution Animal Science and Zoology Cattle Energy Metabolism Biomarkers Food Science |
Zdroj: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia instname |
Popis: | [EN] Peripartal cows mobilize not only body fat but also body protein to satisfy their energy requirements. The objective of this study was to determine the effect of prepartum BCS on blood biomarkers related to energy and nitrogen metabolism, and mRNA and protein abundance associated with AA metabolism and insulin signaling in subcutaneous adipose tissue (SAT) in peripartal cows. Twenty-two multiparous Holstein cows were retrospectively classified into a high BCS (HBCS; n = 11, BCS >= 3.5) or normal BCS (NBCS; n = 11, BCS Y. Liang is a recipient of a doctoral fellowship from the China Scholarship Council (CSC, Beijing, China) to perform his PhD studies at the University of Illinois (Urbana). A. S. Alharthi received a fellowship from King Saud University (Riyadh, Saudi Arabia) to perform his PhD studies at the University of Illinois (Urbana). A. A. Elolimy was recipient of a fellowship from the Higher Education Ministry (Cairo, Egypt) to perform his PhD studies at the University of Illinois (Urbana). We thank Perdue AgriBusiness (Salisbury, MD) for the donation of ProvAAL2 AADvantage during the course of the experiment. The authors declare no conflicts of interest. |
Databáze: | OpenAIRE |
Externí odkaz: |