| Popis: |
By making use of a modified voluntary ingestion procedure, the dosage‐mortality curves for both male and female rats were determined for 4 red squill standards of widely varying potency. The ratio of the LD 50 's for males to the LD 50 's for females was found to be a constant and the slopes of the male and female curves were in each case found to be parallel. It should, therefore, be possible for a bioassayist to determine this constant for his strain of rats, incorporate it in an adjusted dosage schedule and thereafter use both sexes in his squill assays. |
