Appetite control by the tongue-gut axis and evaluation of the role of CD36/SR-B2

Autor: Philippe Besnard, I. Niot
Přispěvatelé: Equipe NuTox (LNC - U1231) ( NUTOX ), Lipides - Nutrition - Cancer [Dijon - U1231] ( LNC ), Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Equipe NuTox (LNC - U1231) (NUTOX), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale (INSERM)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
CD36 Antigens
CD36
Appetite
Biochemistry
SR-B2
MESH: Obesity
MESH: Animals
Receptor
media_common
chemistry.chemical_classification
MESH : Food Preferences
MESH : Tongue
MESH: Tongue
General Medicine
Lipids
3. Good health
MESH : Antigens
CD36
Overconsumption
Appetite control
MESH : Obesity
MESH : Appetite
medicine.medical_specialty
media_common.quotation_subject
Biology
03 medical and health sciences
Food Preferences
Tongue
Internal medicine
medicine
Animals
Humans
Lipid sensor
[SDV.BBM]Life Sciences [q-bio]/Biochemistry
Molecular Biology
Obesity
MESH: Food Preferences
[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry
Molecular Biology
MESH: Humans
MESH: Antigens
CD36
MESH : Humans
Fatty acid
MESH : Lipids
medicine.disease
MESH: Lipids
Gastrointestinal Tract
030104 developmental biology
Endocrinology
chemistry
Membrane protein
biology.protein
MESH: Appetite
MESH: Gastrointestinal Tract
MESH : Animals
MESH : Gastrointestinal Tract
Function (biology)
Zdroj: Biochimie
Biochimie, Elsevier, 2017, 136, pp.27-32. 〈http://www.sciencedirect.com/science/article/pii/S0300908417300421〉. 〈10.1016/j.biochi.2017.02.011〉
Biochimie, Elsevier, 2017, 136, pp.27-32. ⟨10.1016/j.biochi.2017.02.011⟩
ISSN: 0300-9084
DOI: 10.1016/j.biochi.2017.02.011〉
Popis: IF 3.112; International audience; Understanding the mechanisms governing food intake is a public health issue given the dramatic rise of obesity over the world. The overconsumption of tasty energy-dense foods rich in lipids is considered to be one of the nutritional causes of this epidemic. Over the last decade, the identification of fatty acid receptors in strategic places in the body (i.e. oro-intestinal tract and brain) has provided a major progress in the deciphering of regulatory networks involved in the control of dietary intake. Among these lipid sensors, CD36/SR-B2 appears to play a significant role since this membrane protein, known to bind long-chain fatty acid with a high affinity, was specifically found both in enterocytes and in a subset of taste bud cells and entero-endocrine cells. After a short overview on CD36/SR-B2 structure, function and regulation, this mini-review proposes to analyze the key findings about the role of CD36/SR-B2 along of the tongue-gut axis in relation to appetite control. In addition, we discuss whether obesogenic diets might impair lipid sensing mediated by CD36/SR-B2 along this axis.
Databáze: OpenAIRE
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