In Vitro Susceptibilities of Burkholderia mallei in Comparison to Those of Other Pathogenic Burkholderia spp

Autor: D. J. Kenny, Richard W. Titball, P. Russell, S. M. Eley, D. Rogers
Rok vydání: 1999
Předmět:
Zdroj: Antimicrobial Agents and Chemotherapy. 43:2773-2775
ISSN: 1098-6596
0066-4804
DOI: 10.1128/aac.43.11.2773
Popis: The in vitro antimicrobial susceptibilities of isolates of Burkholderia mallei to 16 antibiotics were assessed and compared with the susceptibilities of Burkholderia pseudomallei and Burkholderia cepacia . The antibiotic susceptibility profile of B. mallei resembled that of B. pseudomallei more closely than that of B. cepacia , which corresponds to their similarities in terms of biochemistry, antigenicity, and pathogenicity. Ceftazidime, imipenem, doxycycline, and ciprofloxacin were active against both B. mallei and B. pseudomallei . Gentamicin was active against B. mallei but not against B. pseudomallei . Antibiotics clinically proven to be effective in the treatment of melioidosis may therefore be effective for treating glanders.
Databáze: OpenAIRE