N-terminal probrain natriuretic peptide as biomarker for diagnosis of Kawasaki disease
| Autor: | Alvaro Antonio Perez-Reviriego, Ana Castellano-Martinez, Moises Rodriguez-Gonzalez, Helena Maria Cascales-Poyatos |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Prolonged fever Clinical Biochemistry Diagnostic accuracy 030204 cardiovascular system & hematology Mucocutaneous Lymph Node Syndrome Gastroenterology 03 medical and health sciences Childhood vasculitis 0302 clinical medicine Internal medicine Drug Discovery Natriuretic Peptide Brain Natriuretic peptide Medicine Humans Coronary artery aneurysm business.industry Diagnostic Tests Routine Biochemistry (medical) medicine.disease Prognosis Peptide Fragments medicine.anatomical_structure 030220 oncology & carcinogenesis Biomarker (medicine) Kawasaki disease business Biomarkers Artery |
| Zdroj: | Biomarkers in medicine. 13(4) |
| ISSN: | 1752-0371 |
| Popis: | Kawasaki disease (KD) is a systemic childhood vasculitis with peculiar tropism for the heart. Coronary artery aneurysms are the primary cause of morbidity and mortality in these patients. The timely administration of gammaglobulin decreases the risk for development of coronary artery aneurysms, highlighting the importance of early KD recognition. However, the most significant dilemma in the management of KD is the diagnosis itself. In this article, we review the recent literature focusing on the diagnostic utility of N-terminal probrain natriuretic peptide as a biomarker for diagnosis of KD. The main conclusion is that N-terminal probrain natriuretic peptide is an useful biomarker for KD diagnostic that represents a valuable addition to the current diagnostic workup of patients with suspected KD, increasing the diagnostic accuracy. |
| Databáze: | OpenAIRE |
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