Experimental research of garden spinach extract as a potential anabolic medicinal product
| Autor: | Victor Pyda, Petro Lykhatskyi, Andriy Nykyforuk, Liudmyla Fira |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
Anabolism biology Chemistry Pharmaceutical Science Pharmacy biology.organism_classification food deprivation Experimental research rats 03 medical and health sciences dry extract 0302 clinical medicine protein metabolism spinach garden leaves dry extract food deprivation protein metabolism spontaneous diuresis oxidative stress rats 030220 oncology & carcinogenesis Product (mathematics) oxidative stress Spinach Pharmacology (medical) Food science spontaneous diuresis spinach garden leaves 030304 developmental biology |
| Zdroj: | Pharmacia 67(4): 277-282 |
| ISSN: | 2603-557X 0428-0296 |
| DOI: | 10.3897/pharmacia.67.e56880 |
| Popis: | Disorders of protein metabolism – one of the pathologies, the treatment of which is an urgent problem of modern medicine and pharmacy. The importance of the problem is stipulated due to the prevalence of diseases that are accompanied by a violation of protein metabolism in the body. Restoration of protein resources during such conditions requires adequate intake of structural components from the outside – proteins, amino acids and other biologically active substances-correctors of protein metabolism. In recent decades, much attention has been paid to the discoveries of anabolic agents of natural origin, especially from plants. We conducted research on the study of the anabolic and antioxidant properties of dry extract of spinach garden leaves on the model of food deprivation in rats. Established, that the dry extract at the dose of 100 mg/kg body weight of animals prevents the development of organic disorders of protein metabolism, oxidative stress, prevents a sharp decrease in body weight and slows down the generalized catabolism caused by starvation in rats. Under the influence of the extract on the model of food deprivation, the diuretic function of the kidneys is preserved at the physiological level. |
| Databáze: | OpenAIRE |
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