Modified-release of encapsulated bioactive compounds from annatto seeds produced by optimized ionic gelation techniques
| Autor: | Julián Quintero-Quiroz, Ana María Naranjo-Durán, Gelmy Ciro-Gómez, John Rojas-Camargo |
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| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Alginates Science Diffusion Composite number Phytochemicals chemistry.chemical_element Capsules Calcium 01 natural sciences Article chemistry.chemical_compound Acetic acid 0404 agricultural biotechnology Chemical engineering 010608 biotechnology Multidisciplinary Plant Extracts Bixin Bixaceae Polyphenols 04 agricultural and veterinary sciences 040401 food science Carotenoids chemistry Polyphenol Yield (chemistry) Seeds Drug delivery Medicine Particle size Nuclear chemistry |
| Zdroj: | Scientific Reports Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) |
| ISSN: | 2045-2322 |
| Popis: | To compare the encapsulation of annatto extract by external gelation (EG) and internal gelation (IG) and to maximize process yield (% Y), two central composite designs were proposed. Calcium chloride (CaCl2) concentration (0.3–3.5%), alginate to gelling solution ratio (1:2–1:6); acetic acid (CH3COOH) concentration (0.2–5.0%) and alginate to gelling solution ratio (1:2–1:6) were taken as independent variables for EG and IG respectively. Release studies were conducted under different conditions; morphology, particle size, the encapsulation efficiency (EE), and release mechanism were evaluated under optimized conditions. The optimized EG conditions were 0.3% CaCl2 and 1:1.2 alginate to gelling solution ratio, whereas a 0.3% CH3COOH and 1:5 alginate to gelling solution ratio were optimized conditions for IG. When 20% extract was employed, the highest EE was achieved, and the largest release was obtained at a pH 6.5 buffer. The Peppas–Sahlin model presented the best fit to experimental data. Polyphenol release was driven by diffusion, whereas bixin showed anomalous release. These results are promising for application as modulated release agents in food matrices. |
| Databáze: | OpenAIRE |
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