Emergence of fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli in subjects from Finland
| Autor: | Timo U. Kosunen, Olli-Veikko Renkonen, Hilpi Rautelin |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Adolescent medicine.drug_class Antibiotics Erythromycin Campylobacter coli Microbial Sensitivity Tests medicine.disease_cause Campylobacter jejuni Microbiology 03 medical and health sciences 0302 clinical medicine Anti-Infective Agents Campylobacter Infections medicine Humans Pharmacology (medical) 030212 general & internal medicine Child Finland Norfloxacin Aged Aged 80 and over Pharmacology 0303 health sciences 4-Quinolones biology 030306 microbiology Campylobacter Infant Drug Resistance Microbial Middle Aged biochemical phenomena metabolism and nutrition biology.organism_classification Culture Media 3. Good health Ciprofloxacin Infectious Diseases Child Preschool Gentamicin Research Article medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 35:2065-2069 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.35.10.2065 |
| Popis: | The in vitro susceptibilities of 102 human campylobacter strains isolated between 1978 and 1980 and 100 strains isolated in 1990 to ciprofloxacin, norfloxacin, erythromycin, gentamicin, and doxycycline were examined. The biotypes and heat-stable serotypes of the strains as well as antimicrobial treatments and travel history of the campylobacter-positive patients were also studied. The results indicated that susceptibility to erythromycin, gentamicin, and doxycycline has remained the same during the past 10 years. No gentamicin-resistant strains were found. Resistance to erythromycin was 3% in both groups of strains. However, the number of norfloxacin-resistant strains increased from 4 to 11% in the follow-up period, and ciprofloxacin-resistant strains, which had not occurred 10 years ago, composed 9% of the strains isolated in 1990. Thus, the increase of fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli has been significant in Finland in the past 10 years. |
| Databáze: | OpenAIRE |
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