CAIX regulates extracellular pH and invasion in glioblastoma

Autor:	Proescholdt, MA, Störr, EM, Lohmeier, A, Merrill, MJ, Brawanski, AT
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	ddc: 610 Invasion Electrophysiological monitor Skull base tumors Glioma 610 Medical sciences Medicine Oculomotor nerves Cathepsin B
Zdroj:	64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20130526-20130529; Düsseldorf; DOCMI.13.07 /20130521/ 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20150607-20150610; Karlsruhe; DOCDI.20.04 /20150602/
DOI:	10.3205/15dgnc215
Popis:	Objective: Malignant gliomas are highly invasive tumors. Metabolically these tumors are characterized by glycolysis leading to increased levels of lactic acid. The hypoxia-inducible carbonic anhydrase (CA) IX has been shown to moderate the extrusion of hydrogen ions into the extracellular space. Since[for full text, please go to the a.m. URL] 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Databáze:	OpenAIRE
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